日本語版

Topic hub — 2026-09-19

Getting used to bitterness

People often say they came to like bitter things. What that sentence claims is undetermined until a measurement is chosen. Did the liking rating go up, did the perceived intensity go down, or did the amount consumed rise? The three look like rewordings of each other and move separately once measured.

This page keeps them apart. Repeated exposure raises liking. Frequent drinkers, however, rate bitterness as stronger. The learning starts before birth, while the measured effect fades under follow-up. What follows places each claim on the measurement it actually rides on.

On this page (9 sections)
  1. The liking side moves
  2. The perception side does not move the same way
  3. When does it start
  4. Is exposure enough
  5. Does it last
  6. What was measured and did not move
  7. Read in the encyclopedia
  8. Go deeper in the research notes
  9. Source ledger
↑

What this page establishes

The liking side moves

Start with the largest body of evidence. Across 43 papers and 117 comparisons, repeated exposure raised post-intervention liking against no exposure (SMD 0.35, 17 comparisons, 820 participants) and raised intake as well (SMD 0.23, 21 comparisons, 1130 participants). That is about 0.6 points on a 9-point liking scale and about 10 g for vegetables. The authors themselves write that the effect sizes are small.

repeated dietary exposure increases Liking of vegetables (SMD 0.35 [0.17, 0.53]) and intake (SMD 0.23 [0.07, 0.39]), compared with no exposure. About 0.6 points on a 9-point liking scalesupported

Scope: A meta-analysis of RCT comparisons (43 papers, 117 comparisons). Mainly infants and young children

Note: The effect size is small, and many of the original studies are at high risk of bias. Bitterness is mentioned as a major factor in vegetable rejection, but there is no analysis stratified by bitterness intensity.

Repeated exposure raised post-intervention liking compared with no exposure (SMD 0.35 [0.17, 0.53]; 17 comparisons, 820 participants), and also raised intake (SMD 0.23 [0.07, 0.39]; 21 comparisons, 1130 participants). This corresponds to about 0.6 points of liking on a 9-point scale, and about 10 g of vegetable.
Limitations: Most of the included studies are small and at high risk of bias. Heterogeneity is low (I2 25-29%), but the effect size is small.
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
Limits: The authors state verbatim: "Effect sizes, however, are small, and limited evidence suggests long-term benefits." Follow-up after the intervention was often limited.
Limitations: Follow-up periods were inconsistent; the authors themselves acknowledge limitations in adherence and reporting.
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
8 daily tasting sessions of sweet red pepper significantly increased liking (P = 0.006) and intake (P = 0.03) compared with a no-treatment control. The sticker-reward condition was intermediate, not differing significantly from either group.
Limitations: A single vegetable (sweet red pepper, not strongly bitter). Small sample. Abstract-level reading only.
Source: Modifying children's food preferences: the effects of exposure and reward on acceptance of an unfamiliar vegetable (Wardle J; Herrera ML; Cooke L; Gibson EL, 2003) · abstract checked
Show dataprocess-repeated-exposure —increases→ "Liking of vegetables (SMD 0.35 [0.17, 0.53]) and intake (SMD 0.23 [0.07, 0.39]), compared with no exposure. About 0.6 points on a 9-point liking scale"
claim: clm-repeated-exposure-increases-vegetable-liking / type: sensory / updated: 2026-08-30

That analysis centres on infants and young children, and its vegetables are not stratified by bitterness. It cannot be read straight across as evidence about getting used to bitterness. The adult experiment below gives a result in the same direction with a drink that is bitter.

After a commercial bittersweet beverage was drunk once a day for 7 days at home, pleasantness ratings for it rose by 68%. Ratings for a control stimulus tasted only in the laboratory over the same period did not change. Drinking something inside daily life and tasting it in a booth gave different outcomes.

repeated dietary exposure increases Adult hedonic ratings of a bittersweet beverage (+68% after once-daily consumption at home for 7 days). Meanwhile, a control stimulus tasted only in the laboratory did not changesupported

Scope: Adult volunteers, one commercially available bittersweet beverage (Stein 2003)

Note: A single study. The beverage's composition (presence or absence of caffeine) and n are not reported in the abstract, and the mechanistic attribution (post-ingestive association) remains the authors' speculation.

After consuming a commercially available bittersweet beverage once daily at home for 7 days, hedonic ratings of that beverage rose by 68%, while ratings of a control stimulus tasted only in the laboratory did not change; health-related information did not affect the change in hedonic ratings.
Limitations: The abstract shows neither the beverage's composition (caffeine content) nor the sample size; a single study; the mechanistic attribution is the authors' speculation.
Source: Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage (Stein LJ; Nagai H; Nakagawa M; Beauchamp GK, 2003) · abstract checked
Context: In 20 moderate caffeine consumers, pleasantness ratings of a novel flavored beverage paired with caffeine (CS+) rose gradually across 8 breakfast conditioning trials, while the pleasantness of a beverage paired with placebo (CS-) did not change. The authors conclude that this change 'are best explained in terms of Pavlovian associations between drink flavour and the postingestive effects of caffeine', providing direct experimental support for the post-ingestive mechanism that Stein 2003 could only speculate about.
Limitations: Since the abstract does not describe this beverage as bitter, this does not reproduce the result for bittersweet beverages, but rather contextualizes the acquisition mechanism for caffeinated beverages in general. Despite the change in pleasantness, overall preference did not change.
Source: Flavour liking and preference conditioned by caffeine in humans (Yeomans MR; Durlach PJ; Tinley EM, 2005) · abstract checked
Limits: Health-related information did not affect the perceptual (hedonic) change accompanying exposure itself, but tended to somewhat increase the behavioral measure of acceptability. The authors interpret this as information potentially acting more strongly on behavior than on hedonic evaluation.
Limitations: Stops at a 『傾向』 (in translation: "tendency"), and the abstract does not report statistical significance. The definition and measurement method of the behavioral measure (acceptability) are also absent from the abstract. Full text not reached (Elsevier/Appetite, Unpaywall closed, no repository copy).
Source: Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage (Stein LJ; Nagai H; Nakagawa M; Beauchamp GK, 2003) · abstract checked
Show dataprocess-repeated-exposure —increases→ "Adult hedonic ratings of a bittersweet beverage (+68% after once-daily consumption at home for 7 days). Meanwhile, a control stimulus tasted only in the laboratory did not change"
claim: clm-adult-bitter-beverage-exposure-liking / type: sensory / updated: 2026-08-31

The perception side does not move the same way

If liking rises, it is tempting to conclude that the bitterness is felt less. That is where the measurements stop agreeing.

Frequent consumers of canned coffee beverages are reported to rate bitterness and retronasal aroma more intensely than less frequent consumers. This comes second-hand through a review, and the participant numbers and statistics could not be confirmed, but the direction is the opposite one.

acquired liking — perceived bitterness is associated with: The source reports that frequent consumers of canned coffee beverages rate bitterness and retronasal aroma more strongly than infrequent consumers, and argues this is because daily consumption in everyday life increases familiarity with coffee, which in turn raises sensitivity to sensory attributes.preliminary

Scope: Stratum: literature (a secondhand citation within a review).

Note: A secondhand citation. Content in which Hong 2025 (a review, full text already read) cites Gotow et al. 2015; the original (Gotow et al. 2015) has not been read.

"Gotow et al. (2015) reported that frequent consumers of canned coffee beverages rate bitterness and retronasal aroma more intensely than less frequent consumers. They suggested that frequent consumption in daily life enhances familiarity with coffee, which in turn increases sensitivity..."
Limitations: The original (Gotow et al. 2015) is unread, a secondhand citation, and details such as the number of frequent/infrequent consumers and statistics cannot be confirmed from the review's description.
Show dataconcept-acquired-liking —has_perceived_bitterness_associated_with→ "The source reports that frequent consumers of canned coffee beverages rate bitterness and retronasal aroma more strongly than infrequent consumers, and argues this is because daily consumption in everyday life increases familiarity with coffee, which in turn raises sensitivity to sensory attributes."
claim: clm-w71d2-coffee-frequent-consumers-bitterness-intensity / type: sensory / updated: 2026-09-07

Meanwhile, after two weeks of repeatedly drinking EGCG, a tea catechin, dissolved in water, the same solution was rated lower for bitterness than after repeating water alone. This is a short study of one compound in water and does not extend to cooking or to food in general.

Scope: An evaluation after repeatedly taking EGCG, a type of tea catechin, dissolved in water for 2 weeks

Note: This is a comparison with repeating water alone, and does not show a mechanism of becoming accustomed to all foods.

After repeatedly taking EGCG dissolved in water for 2 weeks, the bitterness rating for the same EGCG solution was lower than after repeating water alone.
Limitations: This is a result from examining a single compound dissolved in water over a short period, and cannot be extended to cooking or food in general.
Show dataprocess-repeated-exposure —can_decrease→ sensation-bitter
claim: clm-egcg-repeated-exposure-bitterness / type: sensory / updated: 2026-08-31

With cheese, what moved was the vocabulary rather than the perception. Korean consumers initially unfamiliar with Emmental, Gorgonzola and Parmigiano Reggiano selected negative terms such as bitterness, off-flavours and lack of balance strongly, and after repeated exposure selected them less often. Whether the bitterness fell or stopped being called a fault is not separated by this measurement.

acquired liking — perceived bitterness is associated with: In a CATA-method cheese survey of Korean consumers, negative sensory characteristics such as bitterness, off-flavors, and poor balance were strongly selected for Emmental, Gorgonzola, and Parmigiano Reggiano, which were initially unfamiliar, but the frequency of selecting these negative terms decreased after repeated consumption.preliminary

Scope: Stratum: literature (a secondhand citation within a review).

Note: A secondhand citation. Content in which Hong 2025 (a review, full text already read) cites Go et al. 2017; the original (Go et al. 2017) has not been read.

"Go et al. (2017) observed that in a CATA test of various natural cheeses, Korean consumers who were initially unfamiliar with cheeses such as Emmental, Gorgonzola, and Parmigiano Reggiano, perceived strong negative sensory characteristics such as bitterness, off-flavors, and a lack of balance. However, after repeated exposure, the frequency of selecting these negative terms decreased."
Limitations: The original (Go et al. 2017) is unread, a secondhand citation, and details such as the number of consumers and the number of repeated exposures cannot be confirmed from the review's description.
Show dataconcept-acquired-liking —has_perceived_bitterness_associated_with→ "In a CATA-method cheese survey of Korean consumers, negative sensory characteristics such as bitterness, off-flavors, and poor balance were strongly selected for Emmental, Gorgonzola, and Parmigiano Reggiano, which were initially unfamiliar, but the frequency of selecting these negative terms decreased after repeated consumption."
claim: clm-w71d2-cheese-repeated-exposure-bitterness-term-decrease / type: sensory / updated: 2026-09-07

Put side by side, getting used to something is not one phenomenon. Rising sensitivity, falling ratings, and changing vocabulary have each been observed, in different studies.

When does it start

The learning begins before anyone sits at a table. Mothers who drank 300 mL of carrot juice 4 days a week for 3 weeks, either in late pregnancy or during the first 2 months of lactation, had infants who at weaning showed fewer negative facial expressions to carrot-flavoured cereal than to plain cereal (prenatal P =.01, via breast milk P =.03). The interactions for intake and feeding time were not significant, and the paper does not characterise carrot as bitter.

perinatal flavor exposure increases Infant acceptance of an exposed flavor during weaning: groups exposed either prenatally or postnatally showed fewer negative facial expressions to carrot-flavored cereal than to plain cerealsupported

Scope: Randomized 3-group design, 47 mother-infant pairs who completed the study. During the last trimester of pregnancy or the first 2 months of breastfeeding, 300 mL of carrot juice 4 days a week for 3 weeks (Mennella 2001)

Note: The target is carrot flavor, not bitterness (no mention of bitter in the text). The group × flavor interaction for intake and feeding duration was not significant. Positioned as contextual material connecting to the acquired-taste line as a foundation for flavor learning in general.

Infants exposed to carrot flavor prenatally (paired t(14) = 2.88, P =.01) or via breast milk (paired t(16) = 2.41, P =.03) showed fewer negative facial expressions to carrot-flavored cereal than to plain cereal, whereas the unexposed control group did not. A group × flavor interaction was found in mothers' enjoyment ratings (F(2,43) = 3.37, P =.04).
Limitations: The groups are small. 7 mothers weaned before testing. Transmission of carrot flavor via amniotic fluid is inference, not demonstration.
Source: Prenatal and postnatal flavor learning by human infants (Mennella JA; Jagnow CP; Beauchamp GK, 2001) · full text checked
Limits: The group × flavor interaction was not significant for cereal intake (F(2,43) = 1.09, P =.34) or feeding time (F(2,43) = 0.88, P =.42), and since the paper does not characterize carrot as bitter, extending this flavor-learning result to bitter foods is inference beyond the paper.
Limitations: The acceptance effect is carried by facial expressions and maternal ratings, not by measured intake.
Source: Prenatal and postnatal flavor learning by human infants (Mennella JA; Jagnow CP; Beauchamp GK, 2001) · full text checked
Show dataprocess-perinatal-flavor-exposure —increases→ "Infant acceptance of an exposed flavor during weaning: groups exposed either prenatally or postnatally showed fewer negative facial expressions to carrot-flavored cereal than to plain cereal"
claim: clm-perinatal-flavor-exposure-increases-acceptance / type: sensory / updated: 2026-08-30

A follow-up using bitterness itself also exists. From single flavour stimuli to fetuses at 32 and 36 weeks through to 3 weeks and 3 years after birth, the bitter kale flavour showed a general tendency to produce more negative facial expressions than the non-bitter carrot flavour (p<0.001). Bitterness is distinguished from other flavours before birth.

perinatal flavor exposure increases Across multiple measurement points from the fetal period (32 and 36 weeks of pregnancy) through after birth (3 weeks and 3 years), the bitter kale-flavored stimulus tended to elicit significantly more negative facial expressions (cry-face gestalt) than the non-bitter carrot-flavored stimulus (p<0.001).supported

Scope: Stratum: food. A single flavor-capsule stimulus (kale or carrot) to the fetus at 32 and 36 weeks of pregnancy, repeated intake from week 36 to delivery, and longitudinal follow-up through 3 weeks and 3 years after birth (the number of codable data points varies by measurement point; final follow-up n=12).

"fetuses in the third trimester exhibit differential facial reactions to a bitter (kale) and a non-bitter (carrot) flavor... Across all measurement points, there is a general tendency for kale flavor to produce more cry-face gestalts (p < 0.001; Table 6)."
Limitations: The number of participants who could be followed up to age 3 had decreased to 12, a small sample size. The authors report that maternal mental health status (anxiety, depression, stress) can also affect facial expressiveness.
Source: Do Human Fetuses Form Long-Lasting Chemosensory Memories? Longitudinal Follow-Up From Fetus to Young Child of Facial Responses to Flavor/Odor Stimuli (Reissland N; Einbeck J; Baguckaite D; Ustun-Elayan B; Schaal B; Blissett J, 2026) · full text checked
Show dataprocess-perinatal-flavor-exposure —increases→ "Across multiple measurement points from the fetal period (32 and 36 weeks of pregnancy) through after birth (3 weeks and 3 years), the bitter kale-flavored stimulus tended to elicit significantly more negative facial expressions (cry-face gestalt) than the non-bitter carrot-flavored stimulus (p<0.001)."
claim: clm-w71c1-perinatal-kale-carrot-cryface / type: sensory / updated: 2026-09-07

Repetition still works. Among 12 children whose mothers repeatedly consumed either kale or carrot flavour in late pregnancy, presenting both odours at age 3 gave significantly fewer negative expressions, within the same child, to the flavour they had been exposed to in utero (p<0.001). That only 12 children were followed to that point cannot be dropped from the reading.

perinatal flavor exposure reduces When kale and carrot odors were presented at age 3 to 12 children of mothers who had repeatedly consumed kale (bitter) flavor in late pregnancy, within the same children, negative facial expressions to the odor of the flavor they had been repeatedly exposed to prenatally were significantly fewer than negative facial expressions to the odor of the flavor they had not been exposed to (p<0.001). The authors interpret this as evidence that fetal chemosensory memory persists for years after birth.supported

Scope: Stratum: food. Repeated intake of kale- or carrot-flavored capsules in late pregnancy (from week 36 to delivery); an olfactory presentation test with a within-subject comparison presenting both odors at age 3 (n=12).

"the 3-year-olds exhibited a significantly reduced rate of negative facial expressions in response to the odor they had been repeatedly exposed to in utero (p < 0.001)... we observed a significant reduction in facial expressions, which could be interpreted as rejection of that vegetable odor when the child had been exposed to it repeatedly in the late stages of pregnancy."
Limitations: Only 12 participants could be followed up to age 3, a small number. The comparison is a within-subject comparison presenting both odors to the same child, and the number of participants per exposure group is not reported in the text.
Source: Do Human Fetuses Form Long-Lasting Chemosensory Memories? Longitudinal Follow-Up From Fetus to Young Child of Facial Responses to Flavor/Odor Stimuli (Reissland N; Einbeck J; Baguckaite D; Ustun-Elayan B; Schaal B; Blissett J, 2026) · full text checked
Show dataprocess-perinatal-flavor-exposure —reduces→ "When kale and carrot odors were presented at age 3 to 12 children of mothers who had repeatedly consumed kale (bitter) flavor in late pregnancy, within the same children, negative facial expressions to the odor of the flavor they had been repeatedly exposed to prenatally were significantly fewer than negative facial expressions to the odor of the flavor they had not been exposed to (p<0.001). The authors interpret this as evidence that fetal chemosensory memory persists for years after birth."
claim: clm-w71c1-perinatal-kale-exposure-reduces-rejection-3y / type: sensory / updated: 2026-09-07

Is exposure enough

Here the claim itself is divided. The claim that acquiring a liking for bitterness requires not mere exposure but an association between the flavour and a post-ingestive reward carries three pieces of evidence pointing in different directions.

acquired liking requires Not mere exposure alone, but the association of flavor with a post-ingestive reward (nutritional or pharmacological)contested

Scope: The acquisition of liking for bitter foods and novel foods in humans

Note: For caffeinated beverages, reward association plus motivational-state dependence is supported, while for vegetables, liking rises from reward-free repeated exposure alone, and no additional benefit from flavor-nutrient conditioning is found (intake even shows a lower SMD of -0.45). The phenomenon (whether liking can be acquired) is separated out into each claim, and this claim addresses only the mechanism. The mechanism may differ by domain (presence or absence of a pharmacological reward).

Context: The authors suggest that the hedonic increase arose 'perhaps through a learned association of flavor with post-ingestive consequences', but the design does not separate mere exposure from association with nutritional/pharmacological consequences.
Limitations: It cannot be determined whether this is mere exposure or post-ingestive reinforcement. An abstract-level reading only.
Source: Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage (Stein LJ; Nagai H; Nakagawa M; Beauchamp GK, 2003) · abstract checked
In the domain of caffeinated beverages, the acquisition and expression of the increase in liking tracked the contingency between caffeine and the fasting/abstinence state, consistent with reward association rather than mere exposure.
Limitations: Domain-specific (pharmacologically active beverages); may not generalize to foods without a drug reward.
Source: Acquisition and extinction of flavour preferences conditioned by caffeine in humans (Yeomans MR; Jackson A; Lee MD; Steer B; Tinley E; Durlach P; Rogers PJ, 2000) · abstract checked
Contradicts: Simple repeated exposure without a contingent reward raised liking for vegetables (SMD 0.35), while flavor-nutrient conditioning produced lower intake than repeated exposure (SMD -0.45 [-0.87, -0.03], P = 0.04; 3 comparisons, 101 participants). In this domain, a post-ingestive nutritional reward added no benefit.
Limitations: The flavor-nutrient comparison relies on only 3 comparisons. Vegetables are not stratified by bitterness. A nutritional reward is pharmacologically different from caffeine.
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
Show dataconcept-acquired-liking —requires→ "Not mere exposure alone, but the association of flavor with a post-ingestive reward (nutritional or pharmacological)"
claim: clm-acquired-bitter-liking-requires-reward / type: mechanism / updated: 2026-08-30

The caffeine evidence supports the association. In 20 moderate caffeine consumers, pleasantness ratings for a novel flavoured drink paired with caffeine rose steadily across 8 conditioning trials, while ratings for the drink paired with placebo did not change. The vegetable evidence runs the other way: simple repeated exposure without contingent reward raised liking (SMD 0.35), and flavour-nutrient conditioning produced lower intake than repeated exposure (SMD -0.45, P = 0.04, 3 comparisons, 101 participants).

The disagreement may come down to different subjects. Whether a pharmacologically active drink and a vegetable belong on one scale cannot be decided here. That is why the claim still carries the contested label.

Does it last

In the follow-up analysis of the same meta-analysis, no effect on liking for novel vegetables remained at the longest follow-up (SMD 0.15, P = 0.41), and where follow-up was measured the effect had generally diminished.

repeated dietary exposure has limited long-term persistence of Improvement in liking: at the longest follow-up point, no effect remained on liking for novel vegetables (SMD 0.15 [-0.21, 0.50], P = 0.41)supported

Scope: A follow-up analysis within the same meta-analysis. Follow-up periods were often short and inconsistent

Note: The authors' overview: 『Effect sizes, however, are small, and limited evidence suggests long-term benefits』. A counter/limiting claim showing the limits of the durability of acquired liking. Durability may be age-window dependent: in 95 infants, the effect was stable up to 3 months later (Remy 2013, linked as contradicts).

At the longest follow-up point, no effect remained on liking for novel vegetables (SMD 0.15 [-0.21, 0.50], P = 0.41), and when measured at follow-up, effects had generally decreased.
Limitations: Few studies measured long-term outcomes, and the range of follow-up periods is wide (up to several years at most).
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
Contradicts: In 95 infants at the start of weaning (6.4 +/- 0.8 months), 10 repeated exposures to a basic artichoke puree raised intake (+63%) and liking (+21%), and verbatim, 'Learning of artichoke acceptance was stable up to 3 mo postexposure.' An adequately powered infant trial incorporating follow-up at 2 weeks, 3 months, and 6 months records persistence of the exposure effect over several months, conflicting with the meta-analysis finding that no effect remains at the longest follow-up point.
Limitations: The stability described explicitly in the abstract covers up to 3 months. Since the abstract does not report the result at 6 months, persistence beyond 3 months is untested here. Infants at the start of weaning are a different population from the older children who form the core of the meta-analysis, so this may reflect an age window rather than a genuine contradiction.
Show dataprocess-repeated-exposure —has_limited_long_term_persistence_of→ "Improvement in liking: at the longest follow-up point, no effect remained on liking for novel vegetables (SMD 0.15 [-0.21, 0.50], P = 0.41)"
claim: clm-exposure-effect-durability-limited / type: sensory / updated: 2026-08-31

The same card carries evidence pointing the other way. In 95 infants at the start of complementary feeding, 10 repeated exposures to artichoke purée raised intake by 63% and liking by 21%, and the acceptance was stable up to 3 months after exposure. Whether this is a difference of age window or a genuine disagreement is not settled.

What was measured and did not move

Measurements that produced no difference are given the same weight as those that did.

Before and after 10 healthy women used a capsaicin oral gel for 14 days, there was no clear statistical change in their ability to identify salty, sweet, sour and bitter tastes or in the intensities they reported. This is a small pilot and is not proof of no effect at all.

repeated dietary exposure does not significantly influence A test conducted after 14 days to distinguish saltiness, sweetness, sourness, and bitterness, and an intensity evaluationpreliminary

Scope: A small pilot study of 10 healthy women using an oral gel containing capsaicin

Note: This is a result in which no difference was found in a trial with few participants, and is not proof that there is no effect at all.

Before and after using the capsaicin-containing gel in the mouth for 14 days, there was no statistically clear change in the performance of distinguishing saltiness, sweetness, sourness, and bitterness, or in the perceived intensity.
Limitations: This is a small pilot study, and there are also limitations in how the comparison group was set up. It is not proof that there is no effect at all.
Source: Effects of Oral Topical Capsaicin Gel on Taste Perception in Healthy Subjects: A Pilot Study (Rupel K; Buoite Stella A; Tamos M; Adamo D; Canfora F; Biasotto M; Di Lenarda R; Ottaviani G, 2025) · full text checked
Show dataprocess-repeated-exposure —does_not_significantly_influence→ "A test conducted after 14 days to distinguish saltiness, sweetness, sourness, and bitterness, and an intensity evaluation"
claim: clm-capsaicin-basic-taste-null-pilot / type: sensory / updated: 2026-08-31

The cultural record

Outside the laboratory, the learning is spoken of as a rule of cooking. In an ethnobotanical study of wild greens on Ikaria, Greece (semi-structured interviews, n=31), the researcher argues that developing a liking for bitterness requires a learning process, and older residents described adding lemon to bitter boiled greens as a culinary necessity. This is description rather than measurement, kept here as a record that getting used to bitterness does not happen only inside one person.

acquired liking is documented in horta vrastacontextual

Scope: Greece, Ikaria Island; ethnobotanical study of wild leafy vegetables (chorta) through semi-structured interviews (n=31).

Note: As the researchers' own analysis, it states 「個人が苦味への嗜好を発展させるには学習過程が必要」 (in translation: “a sort of learning process is required for an individual to develop an appreciation for it”). It records that elderly residents described adding lemon to bitter boiled leafy vegetables (chorta) as 「料理上の必須」 (in translation: “this is consistently perceived as a culinary 'must' by elderly community members”). It connects to existing wild-leafy-vegetable (horta) assets. Descriptions of efficacy in the Blue Zone/longevity context are deliberately excluded from this claim.

The researchers argue that developing an appreciation for bitterness requires a learning process, and record that elderly residents described adding lemon to bitter boiled leafy vegetables as a culinary necessity.
Limitations: The overall focus of the study is dietary patterns in the Blue Zone/longevity context; this claim extracts only the descriptions of learning about bitterness and cooking practices within it. Health-benefit claims are not addressed by this evidence.
Source: Bitter Is Better: Wild Greens Used in the Blue Zone of Ikaria, Greece (Pieroni A; Morini G; Piochi M; Sulaiman N; Kalle R; Haq SM; Devecchi A; Franceschini C; Zocchi DM; Migliavada R; et al., 2023) · full text checked
Show dataconcept-acquired-liking —is_documented_in→ dish-horta-vrasta
claim: clm-h10-pieroni-ikaria-bitter-greens-learned-appreciation / type: cultural / updated: 2026-09-02

Questions people ask

Can an adult come to like bitter things?

Within the scope of this page there is one adult measurement that moved. After a commercial bittersweet beverage was drunk once a day for 7 days at home, pleasantness ratings rose by 68%, while a control tasted only in the laboratory did not change. The abstract gives neither the composition of the drink nor the sample size, and it is a single study.

Does getting used to bitterness mean feeling it less?

The direction depends on the measurement. After two weeks of repeated EGCG intake, bitterness ratings for the same solution fell. Frequent drinkers of canned coffee, on the other hand, are reported to rate bitterness more intensely than infrequent ones. With cheese, the frequency of selecting negative terms fell. Perceiving less, minding less, and naming it differently ride on different measurements on this page.

Will serving bitter vegetables to a child eventually work?

The meta-analytic effect exists and is small: across 43 papers and 117 comparisons, liking SMD 0.35, about 0.6 points on a 9-point scale and about 10 g of intake. At the longest follow-up no effect remained (SMD 0.15, P = 0.41). Yet in infants at the start of complementary feeding, the effect of 10 exposures was stable up to 3 months. Results differ by age and by vegetable, and this page cannot resolve them into one answer.

Are preferences settled before birth?

Not settled, but started. From 32 and 36 weeks of gestation to age 3, the bitter kale flavour tended to produce more negative facial expressions than the non-bitter carrot flavour (p<0.001). At the same time, negative expressions to the odour repeatedly experienced in utero were significantly fewer at age 3 (p<0.001, 12 children). The distinction before birth and the learning before birth sit inside the same study.

What is not known

Read in the encyclopedia

All entries in this hub (3)

Every encyclopedia entry that belongs to this hub, grouped by category. Entries without an English version open in Japanese.

processperinatal flavor exposure · repeated dietary exposure

conceptacquired liking

Go deeper in the research notes

Source ledger

The primary sources and limitations for the claims on this page can be checked from the source links inside each card. The full list is on the Japanesesource ledger.

How to cite this page

Aoki, M. (NIGAMI LAB) (2026). Getting used to bitterness. https://nigamilab.com/en/topics/acquired-taste/

Each claim card has a stable anchor (#clm-…). The dataset is CC BY 4.0; see the data page. Dataset DOI: 10.5281/zenodo.22739101