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horehound

spice or herb / spice-horehound

ホアハウンド / Marrubium vulgare

Horehound is a candidate bitter plant referring to the dried flowering aerial parts of white horehound. Identification in a medicinal assessment is not a recommendation for food use.

On this page (7 sections)
  1. Overview
  2. Sources for this overview (3)
  3. Topic hubs
  4. Follow the connections
  5. Related entries (10)
  6. Composition and content (2)
  7. Culture (1)
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Reading the bitterness

Horehound (Marrubium vulgare, white horehound) refers to the dried flowering aerial parts. An EMA (European Medicines Agency) assessment describes them as bitter and identifies marrubiin, a furan-type labdane diterpene, as contributing to that bitterness.

One review states "M. vulgare has a bitter value of 3.0, acting as the bitter gustative receptores (on the base of the tongue) stimulator". Another review says "Marrubiin is a widely known diterpenoid lactone that constitutes the bitter principle of the horehound and many other medicinal plants", positioning marrubiin as a principal bitter constituent of horehound.

Both descriptions come from reviews synthesizing earlier literature, and neither the basis for calculating the bitter value of 3.0 nor the reference scale can be identified from the review alone. The EMA assessment concerns specifications for medicinal plant material, not a direct sensory or reconstitution test.

The same review gives marrubiin, a constituent implicated in the bitterness of the dried flowering aerial parts, at 0.12–1% (a value the review cites from earlier literature). It also says that drying changes the aroma of M. vulgare, giving it a pungent but pleasant smell and an aromatic taste with bitterness. Like the existing bitter-value figure of 3.0, these are summaries in a review; no sensory values by degree of drying or place of origin are given.

Sources for this overview

  1. Assessment report on Marrubium vulgare L., herba

    European Medicines Agency; Committee on Herbal Medicinal Products / 2013 / government document / full text checked

    Checked for this overview: Used the description of bitterness in dried flowering aerial parts and marrubiin's involvement. / Used the fact that the assessment concerns medicinal specifications, not a sensory test.

  2. Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

    Aćimović M; et al. / 2020 / review / full text checked

    Checked for this overview: Used the review's bitter-value figure of 3.0. / Used the limitation that the basis for the bitter-value calculation cannot be identified. / Figures for total labdane diterpenes and the proportion of marrubiin.

  3. Marrubiin

    Popoola OK; Elbagory AM; Ameer F; Hussein AA / 2013 / review / full text checked

    Checked for this overview: Used the description of marrubiin as a principal bitter constituent.

Follow the connections

horehound →— major bitter compound→ marrubiin

Structured claims — open a section to read each claim's confidence, evidence and limits

Composition and content (2)

horehound — major bitter compound: marrubiincontextual

Scope: The dried flowering aerial parts of Marrubium vulgare

Note: The EMA assessment report records its role in bitterness and a standard of 0.7% or more in the dried herbal drug. This is not a recommendation for culinary use.

Context: The dried flowering aerial parts have bitterness, and the assessment report identifies the furan-type labdane diterpene marrubiin as contributing to it.
Limitations: Not a direct sensory or reconstitution test; a standards context for a medicinal raw material.
Source: Assessment report on Marrubium vulgare L., herba (European Medicines Agency; Committee on Herbal Medicinal Products, 2013) · full text checked
The review states, "M. vulgare has a bitter value of 3.0, acting as the bitter gustative receptores (on the base of the tongue) stimulator," and reports marrubiin as the characteristic labdane-type diterpene (content 0.12-1%).
Limitations: A review, with no independent sensory-test data of its own. The basis for calculating the bitter value of 3.0 and the reference scale cannot be identified from this description alone.
Source: Marrubium vulgare L.: A Phytochemical and Pharmacological Overview (Aćimović M; et al., 2020) · full text checked
A statement that reads: "Marrubiin is a widely known diterpenoid lactone that constitutes the bitter principle of the horehound and many other medicinal plants."
Limitations: A review; the authors themselves did not carry out any new sensory testing or quantitative analysis.
Source: Marrubiin (Popoola OK; Elbagory AM; Ameer F; Hussein AA, 2013) · full text checked
Show dataspice-horehound —has_major_bitter_compound→ compound-marrubiin
claim: clm-horehound-marrubiin / type: composition / updated: 2026-08-31
horehound — composition: marrubiinpreliminary

Scope: Layer: literature. Description from the Composition section of an existing academic review (Aćimović et al. 2020, Molecules).

"M. vulgare accumulates diterpenes of labdane type as principle bitter components, up to 3 mg/g of fresh weight, with marrubiin being the predominant one (0.12–1%) followed by its precursor pre-marrubiin (0.13%)..." Another section: "M. vulgare has a musky odor that changes by drying into a pungent yet pleasant odor and bitter, aromatic taste."
Limitations: This is an integrated description within a review, and the primary measurement conditions (source, extraction method, measurement year) for the value 0.12–1% marrubiin cannot be determined from the review description alone.
Source: Marrubium vulgare L.: A Phytochemical and Pharmacological Overview (Aćimović M; et al., 2020) · full text checked
Show dataspice-horehound —has_composition→ compound-marrubiin
claim: clm-w71f2-horehound-marrubiin-content / type: composition / updated: 2026-09-07

Culture (1)

horehound is used as Spices and herbs that add bitter flavor and aroma to dishes and drinksunverified

Scope: A candidate at the level of general knowledge. Regional and naming differences have not been confirmed.

No source connected — this claim has not been verified yet. It is a general-knowledge placeholder, not a confirmed statement.

Show dataspice-horehound —is_used_as→ "Spices and herbs that add bitter flavor and aroma to dishes and drinks"
claim: clm-spice-horehound-candidate-role / type: cultural / updated: 2026-08-31

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