日本語版

sweetness

sensation / sensation-sweet

甘味

Sweetness from sugars and other substances does more than simply cover bitterness. The balance of sweet and bitter shifts with mixing concentration, the order in which substances reach the tongue, age, and genetic differences among people.

On this page (7 sections)
  1. Overview
  2. Sources for this overview (4)
  3. Topic hubs
  4. Follow the connections
  5. Related entries (10)
  6. Sensory (4)
  7. Mechanism and receptors (2)
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Reading the bitterness

Sweetness does not merely mask bitterness; their balance varies with concentration and conditions of perception. A human psychophysical study mixing brewed coffee with sucrose reported subadditivity in overall taste and flavor intensity even in coffee–sucrose mixtures, with suppression of roughly 30–40% and mutual suppression between the components. The original full text has not been obtained, so this account is limited to the abstract.

In a cocoa-flavored model system using the steviol glycoside rebaudioside A and sucrose, some of sucrose’s bitterness-suppression effect remained even when sweet perception was temporarily blocked with a Gymnema sylvestre extract, according to a study. The result was interpreted as suggesting a peripheral mechanism independent of perceived sweetness; it came from a model system, not actual chocolate food, and the original full text has not been obtained.

Another study reported that mixing acesulfame K or saccharin 1:1 with any of allulose, aspartame, erythritol, fructose, glucose, or sucrose enhanced sweetness by 60–100% and reduced bitterness from acesulfame K or saccharin by 35–63% relative to either alone. Cell-based assays of human bitter and sweet receptors for the same combinations were also reported to match the pattern of sweetness enhancement and bitterness reduction seen in sensory evaluation. The original full texts have not been obtained; this account is limited to abstracts.

A review states that sucrose effectively suppresses mild to moderate bitterness from molecules such as urea, caffeine, propylthiouracil, and quinine, but does not make strongly offensive bitterness acceptable. The same review says that when saccharin and cyclamate are combined, cyclamate blocks the bitter receptors stimulated by saccharin (TAS2R31 and TAS2R43), while saccharin inhibits those activated by cyclamate (TAS2R1 and TAS2R38), producing perceived sweetness with a less bitter aftertaste. These descriptions derive from earlier studies cited by the review.

Sources for this overview

  1. Interactions in caffeine–sucrose and coffee–sucrose mixtures: evidence of taste and flavor suppression

    Calvino Amalia Mirta; García-Medina María Rosa; Cometto-Muniz J Enrique / 1990 / journal article / abstract checked

    Checked for this overview: The report of 30–40% suppression in coffee–sucrose mixtures.

  2. Sweetness-independent bitterness suppression of rebaudioside A by sucrose in a cocoa model

    Lacerda RCC; Junge JY; Andersen GH; Kidmose U; Bolini HMA / 2026 / journal article / abstract checked

    Checked for this overview: The suggestion of a peripheral mechanism because some bitterness suppression remained despite blocked sweet perception.

  3. Sweet-bitter taste interactions in binary mixtures of sweeteners: Relationship between taste receptor activities and sensory perception

    Choi Y; Wong RR; Cha YK; Park TH; Kim Y; Chung SJ / 2024 / journal article / abstract checked

    Checked for this overview: The figures for sweetness enhancement of 60–100% and bitterness reduction of 35–63% in binary sweetener mixtures. / The report that cell-based assay patterns corresponded to sensory-evaluation patterns.

  4. Ingredients to Mask the Aversive Taste of Medicines: Lessons from the Pharmaceutical and Food Industries and Home Remedies Adopted by Caregivers

    Paul S; Yoo O; Locher C; Lim LY / 2026 / review / full text checked

    Checked for this overview: The scope of bitter compounds for which sucrose is effective and its failure against strongly offensive tastes. / Reduced bitter aftertaste from mutual receptor blockade by saccharin and cyclamate.

Follow the connections

coffee brew →— perceived bitterness is s…→ sweetness

sweetness →can reduce the perceived bi…→ bitterness →can be measured separately …→ astringency

bitterness →is reduced by→ sweetness

Structured claims — open a section to read each claim's confidence, evidence and limits

Sensory (4)

coffee brew — perceived bitterness is suppressed by: sweetnesspreliminary

Scope: Layer: food. A human psychophysical test of mixtures of brewed coffee and sucrose (abstract only; concentration and number of participants not confirmed).

The source measured taste-taste and flavor-taste interactions (suppression) for caffeine-sucrose mixtures and coffee-sucrose mixtures. Both mixtures showed broad hypoadditivity in overall taste/flavor intensity, with a suppression rate of roughly 30-40%. Mutual suppression between components was also observed (within the scope of the abstract).
Limitations: The full-text original has not been obtained; this is based on the abstract and a secondary summary. The coffee cultivar and roast conditions used were not confirmed.
Source: Interactions in caffeine–sucrose and coffee–sucrose mixtures: evidence of taste and flavor suppression (Calvino Amalia Mirta; García-Medina María Rosa; Cometto-Muniz J Enrique, 1990) · abstract checked
Show dataingredient-coffee-brew —has_perceived_bitterness_suppressed_by→ sensation-sweet
claim: clm-w67a-coffee-sucrose-flavor-suppression / type: sensory / updated: 2026-09-06
sweetness can reduce the perceived bitterness of bitternesspreliminary

Scope: Layer: solution (cocoa-flavor model system). Split-tongue method, 65 participants (18-35 years old), 2 sessions -- a normal condition and a sweetness-blocked condition.

Note: A result from a model system, not from actual chocolate as a food.

Even when sweet taste reception was blocked with Gymnema sylvestre extract, part of sucrose's effect of suppressing the bitterness of rebaudioside A remained, suggesting a peripheral mechanism.
Limitations: The full text has not been obtained; this is based on the abstract and a secondary summary. A result from a model system, not from actual chocolate as a food.
Source: Sweetness-independent bitterness suppression of rebaudioside A by sucrose in a cocoa model (Lacerda RCC; Junge JY; Andersen GH; Kidmose U; Bolini HMA, 2026) · abstract checked
Show datasensation-sweet —can_reduce_perceived_bitterness_of→ sensation-bitter
claim: clm-w67a-cocoa-model-sweetness-independent / type: sensory / updated: 2026-09-06
sweetness can reduce the perceived bitterness of bitternesspreliminary

Scope: Layer: solution. Binary sweetener mixtures formulated to a target sucrose-equivalent sweetness, with human sensory evaluation.

Note: The bitterness at issue is that of acesulfame K and saccharin themselves, not other bitter components in food.

Mixing acesulfame K or saccharin 1:1 with each of 6 other sweeteners increased sweetness by 60-100% and decreased bitterness derived from acesulfame K or saccharin by 35-63% (both figures at a 50:50 mixture ratio).
Limitations: The full text has not been obtained; this is based on the abstract and a secondary summary. The bitterness at issue is that of the sweeteners themselves, not other bitter components in food.
Show datasensation-sweet —can_reduce_perceived_bitterness_of→ sensation-bitter
claim: clm-w67a-sweetener-binary-bitterness-reduction / type: sensory / updated: 2026-09-06
sweetness can reduce the perceived bitterness of bitternesspreliminary

Scope: Layer: literature (a description in a review).

"Sucrose is effective at reducing mild to moderate bitterness taste of molecules like urea, caffeine, propylthiouracil and quinine but is ineffective in making strongly offensive tastes acceptable, as seen with currently available paediatric liquid formulations like flucloxacillin."
Limitations: The primary study cited as [57] was not checked; this is a review's secondhand account. The passage gives no specific concentration or intensity criterion for 『軽度から中程度』 (in translation: "mild to moderate").
Show datasensation-sweet —can_reduce_perceived_bitterness_of→ sensation-bitter
claim: clm-w72e1-sweet-sucrose-reduces-specific-bitter-compounds / type: sensory / updated: 2026-09-08

Mechanism and receptors (2)

bitterness is reduced by sweetnesspreliminary

Scope: Layer: cell. A cell-based assay using cells expressing human taste receptors.

The results of the cell-based sweet and bitter receptor assay were reported to correspond to the pattern of sweetness enhancement and bitterness reduction observed in the sensory evaluation.
Limitations: The full text has not been obtained; this is based on the abstract and a secondary summary. Details of the receptor types and assay conditions have not been confirmed.
Show datasensation-bitter —is_reduced_by→ sensation-sweet
claim: clm-w67a-sweetener-receptor-activity-correlate / type: mechanism / updated: 2026-09-06
sweetness can reduce the perceived bitterness of bitternesspreliminary

Scope: Layer: cell (receptor-level explanation); literature (description in a review).

"saccharin and cyclamate are intense sweeteners that also activate the bitterness receptors. When consumed together, cyclamate blocks the bitterness receptors (TAS2R31 and TAS2R43) that saccharin stimulates, while saccharin inhibits the bitterness receptors (TAS2R1 and TAS2R38) that cyclamate activates, and the result is a sweetness perception with reduced bitter aftertaste."
Limitations: The primary studies cited as [65] and [66] were not checked; this is a review's secondhand account. The passage provides no quantitative data directly linking receptor pharmacology at the cellular level to actual sensory results.
Show datasensation-sweet —can_reduce_perceived_bitterness_of→ sensation-bitter
claim: clm-w72e1-sweet-saccharin-cyclamate-mutual-receptor-block / type: mechanism / updated: 2026-09-08

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