日本語版

cynaropicrin

compound / compound-cynaropicrin

シナロピクリン

Cynaropicrin is a guaianolide-type sesquiterpene lactone distributed in the bracts, stems, and other parts of artichoke.

Photographs (captions in Japanese)

大きな紫色のアザミ状の花を咲かせたアーティチョークの株の写真

アーティチョーク(Cynara cardunculus var. scolymus)の開花株。cynaropicrin はこの植物の苞・茎などに分布するセスキテルペンラクトンであり、化合物そのものではなく給源植物の写真である。

原料写っているもの: Cynara cardunculus var. scolymus(アーティチョーク)部位・状態: 開花株

写真: Jebulon/ CC0 1.0/ 原画像/ 台帳の原画像

写真の範囲と来歴

被写体の確認: 原典の記載による同定。ingredient-artichoke-globe・ingredient-artichoke-sardegna で使用した写真とは別ファイル(重複回避)。

掲載画像: Wikimedia Commons の原寸ファイル。苦味研究所では切り抜き・色調変更なし。 表示用には幅1200px上限のWebPを配信し、台帳の原画像は上のリンクから確認できます。

On this page (7 sections)
  1. Overview
  2. Sources for this overview (2)
  3. Topic hubs
  4. Follow the connections
  5. Related entries (10)
  6. Composition and content (3)
  7. Sensory (1)
↑

Reading the bitterness

Cynaropicrin is a guaianolide-type sesquiterpene lactone found in artichoke. It is summarized as being present primarily in the edible bracts, where it occurs as a central component among multiple sesquiterpene lactones, and also in small amounts in the stems. One review treats this compound as the component responsible for the typical bitterness of artichoke, but this positioning is a synthesis of multiple primary research findings and is not based on a sensory reconstruction assay that measured cynaropicrin's individual contribution.

Beyond the edible flower buds, European evaluation documents address the dried leaves (from Cynara cardunculus) used as a medicinal product. These documents summarize the bitter sesquiterpene lactones as comprising 0.4% of leaf mass, of which cynaropicrin comprises 47–83%; existing reports that cynaropicrin is most abundant in young leaves are also cited. However, this represents a secondary citation within the evaluation document and has not been established by direct sensory testing to show primary contribution; this data should be distinguished as coming from a plant part distinct from the edible flower buds.

Sources for this overview

  1. Globe Artichoke (Cynara scolymus L.) By-Products in Food Applications: Functional and Biological Properties

    Colombo R; Moretto G; Pellicorio V; Papetti A / 2024 / review / full text checked

    Checked for this overview: Summary of presence as a principal component in bracts and low-level presence in stems / The review's statement that cynaropicrin is the component responsible for typical bitterness, and clarification that this is not based on sensory reconstruction testing

  2. Assessment report on Cynara cardunculus L. (syn. Cynara scolymus L.), folium

    European Medicines Agency; Committee on Herbal Medicinal Products / 2018 / government document / full text checked

    Checked for this overview: Summary of bitter sesquiterpene lactones in leaves at 0.4%, of which cynaropicrin comprises 47–83%

Follow the connections

globe artichoke →contains→ cynaropicrin

cynaropicrin →contributes to→ bitterness →can be measured separately …→ astringency

artichoke leaf →— major bitter compound→ cynaropicrin

Structured claims — open a section to read each claim's confidence, evidence and limits

Composition and content (3)

globe artichoke contains cynaropicrinsupported

Scope: Artichoke's bracts and stem

Note: Content differs by plant part, so no single concentration figure is given.

States that the bracts contain several sesquiterpene lactones, mainly cynaropicrin, and that the stem also contains a low amount of cynaropicrin.
Limitations: A review; the conditions of the individual primary studies are not uniform.
Source: Globe Artichoke (Cynara scolymus L.) By-Products in Food Applications: Functional and Biological Properties (Colombo R; Moretto G; Pellicorio V; Papetti A, 2024) · full text checked
Show dataingredient-artichoke-globe —contains→ compound-cynaropicrin
claim: clm-artichoke-cynaropicrin / type: composition / updated: 2026-08-31
artichoke leaf — major bitter compound: cynaropicrincontextual

Scope: The EMA assessment report on the dried leaf of Cynara cardunculus

Note: The assessment report identifies 47-83% of the leaf's 0.4% bitter sesquiterpene lactones as cynaropicrin. A secondary record states it is higher in young leaves.

Context: Of the leaf's 0.4% bitter sesquiterpene lactones, 47-83% is cynaropicrin, and it summarizes an earlier report that this is highest in young leaves.
Limitations: Not a direct sensory test showing the dominant contribution share. The edible receptacle should not be confused with the leaf.
Source: Assessment report on Cynara cardunculus L. (syn. Cynara scolymus L.), folium (European Medicines Agency; Committee on Herbal Medicinal Products, 2018) · full text checked
Show dataingredient-artichoke-leaf —has_major_bitter_compound→ compound-cynaropicrin
claim: clm-artichoke-leaf-cynaropicrin / type: composition / updated: 2026-08-31
artichoke leaf — major bitter compound: cynaropicrinsupported

Scope: A literature review on the bitterness of artichoke (genus Cynara) plants.

Verbatim (original English): "The bitter taste of artichoke plants is attributed to its high content of sesquiterpene lactones, especially of cynaropicrin." The following sentence: "Cynaropicrin contributes to approximately 80% of the characteristic bitter taste of artichoke, which is associated with the activation of bitter sensory receptors."
Limitations: A review article; the individual primary study underlying the approximately 80% bitterness figure is not identified within this text.
Show dataingredient-artichoke-leaf —has_major_bitter_compound→ compound-cynaropicrin
claim: clm-w55-cynaropicrin-artichoke-bitter-review / type: composition / updated: 2026-09-03

Sensory (1)

cynaropicrin contributes to bitternesssupported

Scope: Artichoke's characteristic bitterness

Note: A review's synthesis of primary research.

A review states that cynaropicrin is responsible for artichoke's characteristic bitterness.
Limitations: Not a sensory reconstitution study that directly measured its contribution.
Source: Globe Artichoke (Cynara scolymus L.) By-Products in Food Applications: Functional and Biological Properties (Colombo R; Moretto G; Pellicorio V; Papetti A, 2024) · full text checked
Show datacompound-cynaropicrin —contributes_to→ sensation-bitter
claim: clm-cynaropicrin-bitter / type: sensory / updated: 2026-08-31

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