化合物 / compound-spilanthol

spilanthol

Unsaturated alkylamide prominent in Acmella oleracea

別名: spilanthol（en）

主張（5）

spilanthol is_associated_with Tingling, pungency and numbing in the mouth支持あり

範囲: Acmella and spilanthol literature summarized by the cited sources

注記: Intensity, time course and human dose-response are not yet recorded here.

Reviews Acmella chemistry and identifies alkylamides as a major constituent group linked to the plant's uses.

限界: The abstract does not provide human sensory dose-response data.

文脈: The article's background identifies oral tingling, pungency and numbing as sensations induced by spilanthol.

限界: The experiment itself did not measure these sensations in humans.

出典: Spilanthol Enhances Sensitivity to Sodium in Mouse Taste Bud Cells（Xu J; Lewandowski BC; Miyazawa T; Shoji Y; Yee K; Bryant BP, 2019）・抄録確認

spilanthol enhanced Responses to NaCl in isolated mouse taste-bud cells予備的

範囲: Mouse cells and trigeminal neurons at tested micromolar concentrations

注記: Do not infer a human salt-enhancement claim from this experiment.

Perithreshold spilanthol enhanced responses to 140 and 200 mM NaCl in isolated mouse taste-bud cells.

限界: Human sensory effect and culinary utility are untested here.

出典: Spilanthol Enhances Sensitivity to Sodium in Mouse Taste Bud Cells（Xu J; Lewandowski BC; Miyazawa T; Shoji Y; Yee K; Bryant BP, 2019）・抄録確認

spilanthol is_associated_with tingling支持あり

範囲: Oral spilanthol exposure described in the literature background

注記: A human time-intensity study is still needed in the database.

The paper's literature-grounded premise states that spilanthol can induce tingling in the mouth.

限界: The experiment did not quantify human tingling.

出典: Spilanthol Enhances Sensitivity to Sodium in Mouse Taste Bud Cells（Xu J; Lewandowski BC; Miyazawa T; Shoji Y; Yee K; Bryant BP, 2019）・抄録確認

spilanthol is_associated_with pungency支持あり

範囲: Oral spilanthol exposure described in the literature background

注記: A human time-intensity study is still needed in the database.

The paper's literature-grounded premise states that spilanthol can induce pungency in the mouth.

限界: The experiment did not quantify human pungency.

出典: Spilanthol Enhances Sensitivity to Sodium in Mouse Taste Bud Cells（Xu J; Lewandowski BC; Miyazawa T; Shoji Y; Yee K; Bryant BP, 2019）・抄録確認

spilanthol is_associated_with numbing支持あり

範囲: Oral spilanthol exposure described in the literature background

注記: A human time-intensity study is still needed in the database.

The paper's literature-grounded premise states that spilanthol can induce numbing in the mouth.

限界: The experiment did not quantify human numbing.

出典: Spilanthol Enhances Sensitivity to Sodium in Mouse Taste Bud Cells（Xu J; Lewandowski BC; Miyazawa T; Shoji Y; Yee K; Bryant BP, 2019）・抄録確認

Acmella oleracea contains spilanthol確立

範囲: Acmella oleracea plant material reviewed in the cited sources

注記: Content varies by organ, origin and extraction; those factors require measurement records.

The review identifies alkylamides as a major Acmella constituent group and centers spilanthol in the plant literature.

限界: Primary quantitative studies should be attached for organ-specific content.

文脈: The Mahidol medicinal-plant page explicitly names spilanthol as the relevant active constituent of ผักคราดหัวแหวน (Acmella oleracea).

限界: Secondary source.

出典: การสกัดผักคราดหัวแหวน（Mahidol University Medicinal Plant Information Center, 2019）・全文確認