受容体 / receptor-tas2r39
TAS2R39
Human bitter taste receptor subtype activated by galloylated tea catechins and many (iso)flavonoids
関連をたどる
茶カテキン類 →活性化する→ TAS2R39
機構・受容体（1）
茶カテキン類はTAS2R39を活性化する支持あり
範囲: Cell-based assay; clear responses to 300 uM ECg and EGCg; ECg strongest followed by EGCg; EC and EGC much weaker
注記: Single concentration (300 uM) reported in abstract; receptor tuning is broad (many flavonoids also activate TAS2R39).
hTAS2R39-expressing cells showed a clear response to 300 uM of either ECg or EGCg; the response to ECg was the strongest among tested catechins, followed by EGCg, while EC and EGC responses were much weaker.
限界: Single reported concentration (300 uM); in vitro receptor response, not a direct bitterness measurement.
出典: Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39（Narukawa M; Noga C; Ueno Y; Sato T; Misaka T; Watanabe T, 2011） ・抄録確認
文脈: 70 of a large set of structurally similar (iso)flavonoids activated hTAS2R39 with activation thresholds spanning 0.12-500 uM, indicating broad receptor tuning; the abstract does not name individual tea catechins.
限界: Catechin-specific values not visible at abstract level; used only as tuning context.
出典: Bitter taste receptor activation by flavonoids and isoflavonoids: modeled structural requirements for activation of hTAS2R14 and hTAS2R39（Roland WS; van Buren L; Gruppen H; Driesse M; Gouka RJ; Smit G; Vincken JP, 2013） ・抄録確認
データを表示
compound-catechins —activate→ receptor-tas2r39claim: clm-galloylated-catechins-activate-tas2r39 / type: mechanism / 更新: 2026-08-30